Systemic Lupus Erythematosus (skin, joints, kidneys, heart, brain, red blood cells, other).Sjögren’s syndrome (salivary glands, tear glands, joints).Scleroderma (skin, intestine, less commonly lungs, kidneys).Rheumatoid arthritis (joints, less commonly lungs, skin, eyes).Polymyalgia rheumatica (large muscle groups).Antiphospholipid antibody syndromes (blood cells).Ulcerative colitis (gastrointestinal tract)Įxamples of rheumatological systemic autoimmune diseases.Primary biliary cholangitis, formerly known as primary biliary cirrhosis (liver).Guillain-Barre syndrome (nervous system).Crohn’s disease (gastrointestinal tract).Coeliac disease (gastrointestinal tract).Examples of localised (organ specific) autoimmune diseases These diseases are often managed by clinical immunology/allergy specialists and/or rheumatologists. They can be broadly classified into rheumatological disease and vasculitis disorders. Systemic autoimmune diseases can affect many body organs and tissues at the same time. These diseases are often managed by organ-specific medical specialists, such as endocrinologists, gastroenterologists, neurologists or rheumatologists. Whilst localised (organ specific) autoimmune diseases mainly affect a single organ or tissue, the effects frequently extend to other body systems and organs. Localised (organ specific) autoimmune diseases Sometimes a biopsy of affected tissues may be required for diagnosis. How are autoimmune diseases diagnosed?Īutoimmune diseases are usually diagnosed using a combination of clinical history, blood tests (autoantibodies, inflammation, organ function) and other investigations such as x-rays. Other factors such as infections and some drugs may also play a role in triggering autoimmune diseases. In many cases there appears to be some inherited tendency. The causes of autoimmune diseases are unknown.
Less commone autoimmune diseases include systemic lupus erythematosus (SLE), also known as lupus, and vasculitis disorders (inflammation of blood vessels). They affect around 5% of people and are an important health issue in Australia and New Zealand:Ĭommon autoimmune diseases include thyroiditis, rheumatoid arthritis and diabetes. Autoimmune diseases include common and rare diseasesĪutoimmune diseases are a broad range of more than eighty related disorders, ranging from common to very rare. In autoimmune diseases the immune system produces antibodies that attack the body's own cells, tissues and organs, resulting in inflammation and damage. The main role of the immune system is to fight foreign invaders such as bacteria, moulds and viruses. ASCIA PCC Autoimmune diseases 2019 111.75 KB
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